This study aims to provide all the necessary keys to understanding the new round of multilateral trade negotiations set off by the World Trade Organization members in Doha on November 14, 2001. It first presents the circumstances that framed the conference, enabling a new round of talks to begin. After the failure of the Ministerial Conference in Seattle, serious doubts indeed hovered as to whether new multilateral trade talks could be launched. Nevertheless, various factors, such as improved transatlantic relations, consideration of the demands of developing countries and civil society, better Conference preparation and the events of September 11 all created a favorable context for Doha. The study then proceeds to describe the characteristics of the new negotiation round and the stakes involved. In drafting the Doha Declaration, so many last-minute diplomatic compromises were made that the document is complex to interpret, even for the negotiators themselves. How the negotiations will be organized from a practical standpoint is also unclear, and warrants clarification. This study thus summarizes the various issues slated for negotiation and what is at stake, as well as the organization and main deadlines for negotiation. Lastly, it analyzes the current state of negotiations and perspectives in view, without going into detail or predicting the future. At a time when WTO members are in the process of negotiation, any conclusion in this regard would quickly be outdated. However, this study reveals that the context that prevailed at Doha no longer exists, and that today the progress of negotiations has run up against several obstacles, as can be seen in the difficulties they are encountering at this early stage.